Molecular mechanisms of induction of persistent changes by estrogenic chemicals on female reproductive tracts and external genitalia
S Miyagawa, M Sato, T Iguchi - The Journal of steroid biochemistry and …, 2011 - Elsevier
The effects of environmental endocrine-disrupting chemicals (EDCs) are a great and
growing concern for human and animal development and life. The reproductive organs are
considered as a primary target of EDCs, yet the effects on reproductive organs can extend to
other body systems. Perinatal diethylstilbestrol (DES)-exposed mice exhibit various
reproductive organ abnormalities. The perinatal DES-exposure model has allowed insight
into our understanding of the mechanisms of persistent reproductive organ abnormalities …
growing concern for human and animal development and life. The reproductive organs are
considered as a primary target of EDCs, yet the effects on reproductive organs can extend to
other body systems. Perinatal diethylstilbestrol (DES)-exposed mice exhibit various
reproductive organ abnormalities. The perinatal DES-exposure model has allowed insight
into our understanding of the mechanisms of persistent reproductive organ abnormalities …
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